Gemifloxacin (By mouth)
Gemifloxacin Mesylate (jem-i-FLOX-a-sin MES-i-late)
Treats lung infections that are caused by bacteria. This medicine is a fluoroquinolone antibiotic.
FactiveThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:You should not use this medicine if you have had an allergic reaction to gemifloxacin or to any other fluoroquinolone antibiotic (such as ciprofloxacin, gatifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, Avelox®, Cipro®, Floxin®, Levaquin®, Noroxin®, or Zymar®).
How to Use This Medicine:
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- You may take this medicine with or without food. Swallow the tablet whole. Do not crush, break, or chew it.
- If you use antacids, sucralfate (Carafate®), or mineral supplements and multivitamins with iron or zinc, take them at least 3 hours before or 2 hours after you take gemifloxacin.
- Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.
- Drink extra fluids so you will pass more urine while you are using this medicine. This will keep your kidneys working well and help prevent kidney problems.
- This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are using a steroid medicine (such as dexamethasone, methylprednisolone, prednisone, prednisolone, Medrol®, or Decadron®). Using a steroid together with this medicine may increase your chance of having tendon problems.
- Make sure your doctor knows if you are also using erythromycin, probenecid (Benemid®), a blood thinner (such as warfarin, Coumadin®), medicine for depression (such as amitriptyline, imipramine, Norpramin®, or Vivactil®), or medicine to treat an abnormal heart rhythm (such as amiodarone, procainamide, quinidine, sotalol, Betapace®, Cordarone®, Cardioquin®, Procan®, Procanbid®, Pronestyl®, Quinaglute®, or Quinidex®).
- Tell your doctor if you are using a phenothiazine medicine (such as Compazine®, Phenergan®, Serentil®, or Thorazine®). Make sure your doctor knows if you are also using antacids that contain magnesium or aluminum (such as Maalox®, Mylanta®), iron supplements, multivitamins with iron or zinc, or sucralfate (Carafate®).
Warnings While Using This Medicine:
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, heart rhythm problems (such as QT prolongation), chest pain, low potassium or low magnesium levels in your blood, a slow heartbeat, or a recent heart attack. Make sure your doctor knows if you are receiving dialysis, or if you have a history of seizures.
- If you have severe diarrhea, ask your doctor before taking any medicine to stop the diarrhea.
- This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.
- This medicine may rarely cause inflammation or tearing of a tendon (the cord that attaches muscles to bones). This can occur while you are taking the medicine or after you finish taking it. The risk of having tendon problems may be increased if you are over 60 years of age, are using steroid medicines (e.g., dexamethasone, prednisolone, prednisone, Medrol®), have severe kidney problems, have a history of tendon problems (e.g., rheumatoid arthritis), or if you have received an organ transplant (e.g., heart, kidney, or lung). Stop using this medicine and check with your doctor right away if you have sudden pain or swelling in a tendon after exercise (e.g., ankle, back of the knee or leg, shoulder, elbow, or wrist), bruise more easily after an injury, or are unable to bear weight or move the affected area. Refrain from exercise until your doctor says otherwise.
- This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
- Blistering, peeling, or red skin rash.
- Diarrhea, or blood in your stool.
- Fast, pounding, or uneven heartbeat.
- Lightheadedness or fainting.
- Muscle pain or tenderness, new problems with movement, or numbness or tingling anywhere in your body.
- Seeing, hearing, or feeling things that are not there.
- Seizures, trouble thinking clearly, or feeling very shaky, restless, or nervous.
- Swelling or sudden pain in your shoulder, elbow, hand, wrist, or in the back of your knee or ankle.
- Unexplained fever.
- Unusual bleeding, bruising, or weakness.
- Yellowing of your skin or the whites of your eyes.
If you notice these less serious side effects, talk with your doctor:
- Mild nausea or vomiting.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 1/4/2011
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