Chlorambucil (By mouth)
Treats cancer of the blood (leukemia) and lymph systems.
LeukeranThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:You should not receive this medicine if you have had an allergic reaction to chlorambucil or certain other cancer medicines, or if you are pregnant.
How to Use This Medicine:
- Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
- Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
- Store this medicine in the refrigerator.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you have had any other chemotherapy or radiation therapy within the past 4 weeks.
- Talk to your doctor before getting flu shots or other vaccines while you are receiving this medicine. Vaccines may not work as well, or they could make you ill while you are using this medicine.
Warnings While Using This Medicine:
- Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.
- If you plan to have children, talk with your doctor before using this medicine. Some men and women using this medicine have become infertile (unable to have children).
- Make sure your doctor knows if you are breastfeeding, or if you have a history of seizures or head injury.
- Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments.
- This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
- Blistering, peeling, red skin rash.
- Dark-colored urine or pale stools.
- Fever, chills, cough, sore throat, and body aches.
- Nausea, vomiting, loss of appetite, pain in the upper stomach.
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
- Painful or difficult urination.
- Seizures or tremors.
- Sores, ulcers, or white patches on your lips or mouth.
- Uncontrollable muscle movements or twitching.
- Unusual bleeding, bruising, or weakness.
- Unusual lumps under your skin.
- Yellow skin or eyes.
If you notice these less serious side effects, talk with your doctor:
- Changes in your menstrual periods.
- Confusion, agitation.
- Mild nausea, vomiting, diarrhea.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 1/4/2011
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