Cyclobenzaprine (By mouth)
Treats pain and stiffness caused by muscle spasms.
Flexeril, Amrix, Fexmid, Cyclobenzaprine Comfort PacThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:You should not use this medicine if you have ever had an allergic reaction to cyclobenzaprine, or if you have an overactive thyroid, heart rhythm problems, heart failure, or a recent heart attack. You should not use this medicine if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.
How to Use This Medicine:
Long Acting Capsule, Tablet
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- You may take this medicine with or without food.
- Swallow the extended-release capsule whole. Do not crush, break, or chew it.
- This medicine is not for long-term use.
If a dose is missed:
- If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are using guanethidine (Ismelin®) or tramadol (Ultram®, Ultracet®).
- Tell your doctor if you are using any medicines that make you sleepy. These include sleeping pills, cold and allergy medicine, narcotic pain relievers, and sedatives.
- Do not drink alcohol while you are using this medicine.
Warnings While Using This Medicine:
- Make sure your doctor knows if you are pregnant or breastfeeding, or if you have liver problems, glaucoma, or problems with urination.
- This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Cyclobenzaprine may cause dryness of the mouth, nose, and throat. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.
- If your symptoms do not improve or if they get worse, call your doctor.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
- Fast, pounding, or irregular heartbeat.
- Not urinating for more than 6 hours.
- Seizures or tremors.
- Severe drowsiness, fainting, or confusion.
If you notice these less serious side effects, talk with your doctor:
- Blurred vision.
- Constipation or nausea.
- Dry mouth or throat.
- Unpleasant taste.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 1/4/2011
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